Type-2 Diabetes Mellitus: A Review of Current Trends

Diabetes mellitus type 2 is a chronic metabolic condition whose incidence has been continuously growing around the world. As result of this tendency, it quickly becoming an epidemic in some parts world, with number individuals affected anticipated to double next decade as world's population ages, adding already existing load on healthcare providers, particularly poor developing countries. World Health Organization (WHO) guidelines are still used for screening and diagnosis, which include both clinical laboratory characteristics. There currently no cure disease; however, therapy options lifestyle changes, obesity management, oral hypoglycemic medications, insulin sensitizers such metformin, biguanide that reduces resistance first line medication especially obese patients. The traditional herbal medicine like garlic, neem, bitter gourd, aloe vera, onion, methi, amla, jamun, baheda etc. also treatment diabetes. Other effective includes non-sulfonylurea secretagogues, thiazolidinediones, alpha glucoside inhibitors, insulin. Recent research into biology diabetes led development new medications glucagon-like peptide 1 analogues: dipeptidyl peptidase sodium glucose cotransporter 11-hydroxysteroid dehydrogenase releasing glucokinase activators. novel drug delivery improves by inhaled Keywords: Type mellitus, complications, Antidiabetic newer drugs, drugs